The Johns Hopkins Brain Injury Outcomes (BIOS) Division is a clinical trial coordinating center (data management, imaging reading, and enrollment) within the Johns Hopkins School of Medicine Dept. of Neurology. Its focus is to provide multicenter management to clinical trials evaluating therapeutic, preventive, and diagnostic interventions. Led by Dr. Daniel Hanley, BIOS has unique expertise in the coordination and management of trials investigating rare neurologic disorders, acute neurologic ICU conditions, rehabilitation, and functional outcomes. Since the 1990s, BIOS has coordinated international, federally funded, and industry-sponsored trials across a range of conditions for investigators at academic center across the United States.